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Don’t fret about the site taking a little off the top — 100 percent of all sponsor donations go directly to charity.

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How to Help: Contribute quality baby and school supplies to either the Boston or Philadelphia office, host a clothing drive in your neighborhood or donate.

Gastonia, North Carolina Who they are: It’s rare that volunteers get to see how their personal contributions make a difference. Mobilizing community sewing circles across the country, WUA encourages volunteers to crochet or knit their own 7” by 9” rectangles and mail them to their local chapters.

While the organization provides services for children of all ages, it maintains a strong focus on the under-3 demographic, providing strong nutrition and clean water programs for kids as well as pregnancy support, nutrition education and HIV-prevention programs for their parents.

Two thirds of neonatal and young child deaths — over 6 million deaths every year — are preventable.

Operating with little overhead, the organization has earned a four-star rating for financial health and fiscal effectiveness from the watchdog group, Charity Navigator.

That means your donations go to putting school supplies in the hands of needy youngsters and not to superfluous projects.Connecting the two is the simple mission behind Cradles to Crayons.While C2C doesn’t operate any outlandish or particularly unique programs, it earns a spot on our list because of how efficiently it carries out its duties.With programs in more than 120 countries, including right here, Save the Children focuses on providing long-term hunger relief, education, literacy, nutrition, basic hygiene and health programs to those who need it most.Save the Children wins a spot on our list not only because of the programs it runs but also because of how efficiently the organization operates.The organization estimates that it can save literally millions of lives with enough support. Worldwide Who they are: One of the most world-renowned international adoption programs, this organization has placed nearly 7,000 children from 28 nations around the world.

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